World-Class ADC Linkers Manufacturing
ADC Linkers Manufacturers in India
Pharmaceutical ADC Linkers Manufacturing and Supply
Shilpa Pharma is a globally trusted CDMO and one of the leading ADC linkers manufacturers in India, supporting pharmaceutical and biotech companies across the full spectrum of Antibody-Drug Conjugate (ADC) development. We specialize in the large-scale manufacturing and supply of high-quality antibody drug conjugate linkers, designed to meet the stringent requirements of clinical and commercial ADC programs.
Our state-of-the-art cGMP facilities are approved by USFDA, EU GMP, ANVISA, COFEPRIS, TGA, PMDA, and KFDA, ensuring full regulatory acceptance for international markets. These globally compliant facilities enable the safe, scalable, and reproducible manufacturing of ADC linkers with precise control over chemical stability, release mechanisms, and conjugation performance.
With deep expertise in ADC drug development and process chemistry, Shilpa Pharma provides end-to-end support—from linker design optimization and impurity profiling to bulk manufacturing and secure global supply. Our integrated capabilities ensure seamless alignment with payload chemistry and conjugation strategies, accelerating successful ADC development.
Partner with Shilpa Pharma, where regulatory excellence, scientific precision, and supply reliability power global ADC innovation.
Complete Range of ADC Linkers
| S. No | Product Name | CAS No | Enquire |
|---|---|---|---|
| 1 | Boc-Val-Cit-PAB | 870487-09-5 | Enquire Now |
| 2 | DBCO-Maleimide | 1395786-30-7 | Enquire Now |
| 3 | DBCO-NHS ester | 1353016-71-3 | Enquire Now |
| 4 | Fmoc-Ala-Ala-Asn-PAB-PNP | 18345-16-06-1 | Enquire Now |
| 5 | Fmoc-Gly-Gly-D-Phe-OtBu | 2749985-44-0 | Enquire Now |
| 6 | Fmoc-Gly-Gly-Phe-OH | 160036-44-2 | Enquire Now |
| 7 | Fmoc-Gly3-Val-Cit-PAB-PNP | 2647914-16-5 | Enquire Now |
| 8 | Fmoc-Phe-Lys(Trt)-PAB-PNP | 1116086-09-9 | Enquire Now |
| 9 | Fmoc-Val-Cit-PAB-OH | 159858-22-7 | Enquire Now |
| 10 | Fmoc-Val-Cit-PABC-PNP | 863971-53-3 | Enquire Now |
| 11 | Mal-amido-(CH2COOH)2 | 207613-14-7 | Enquire Now |
| 12 | Mal-amido-PEG8-acid | 1334177-86-4 | Enquire Now |
| 13 | Mal-heptanoic NHS ester | 55750-63-5 | Enquire Now |
| 14 | Mal-PEG1-NHS Ester | 1807518-72-4 | Enquire Now |
| 15 | Mal-PEG2-Val-Cit-PABA-PNP | 1345681-52-8 | Enquire Now |
| 16 | Mal-PEG4-Val-Cit-PAB-OH | 2055041-39-7 | Enquire Now |
| 17 | Mal-PEG6-NHS ester | 1599472-25-9 | Enquire Now |
| 18 | MC-Val-Ala-PAB | 1870916-87-2 | Enquire Now |
| 19 | Mc-Val-Cit-PABC-PNP | 159857-81-5 | Enquire Now |
| 20 | N-(6-Maleimidocaproyl)succinimide (EMCS) | 55750-63-5 | Enquire Now |
| 21 | N-Succinimidyl 4-(2-pyridyldithio)butanoate (SPDB) | 115088-06-7 | Enquire Now |
| 22 | NH2-PEG6-Val-Cit-PAB-OH | 2055024-60-5 | Enquire Now |
| 23 | Phe-Lys(Fmoc)-PAB | 2149584-03-0 | Enquire Now |
| 24 | Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC) | 64987-85-5 | Enquire Now |
| 25 | Val-Cit-PAB-OH | 159857-79-1 | Enquire Now |
| 26 | mc-Gly-Gly-Phe | 1599440-15-9 | Enquire Now |
| 27 | mc-Gly-Gly-Phe-Gly | 2413428-36-9 | Enquire Now |
| 28 | mc-Val-Ala-PAB-PNP | 1639939-40-4 | Enquire Now |
Disclaimer
The content on this website is for general informational purposes only. While we strive for accuracy, Shilpa Pharma makes no warranties regarding the completeness, reliability, or suitability of the information. For detailed product specifications, regulatory documentation, or inquiries, please contact us directly.
Global Leaders in ADC Linkers Manufacturing
Choosing Shilpa Pharma means choosing reliability, quality, and innovation. We deliver not just products, but long-term value that strengthens your business at every step.
Globally Compliant Manufacturing
ADC linkers are manufactured in cGMP facilities compliant with USFDA, EU GMP, ANVISA, COFEPRIS, TGA, PMDA, and KFDA.
Integrated ADC Development Expertise
Strong capabilities across antibody-drug conjugate (ADC) development, linker chemistry, and process scale-up.
High Purity & Stability Control
Advanced analytical systems ensure high-purity ADC linkers with strict impurity and genotoxic risk management.
Optimized Conjugation Performance
Linkers are engineered for consistent conjugation efficiency and downstream ADC performance.
Global Supply & Reliability
Recognized among trusted ADC linkers manufacturers, delivering secure and scalable global supply.
Oncology-Focused CDMO Services
A preferred partner for global ADC drug development and commercial manufacturing programs.
Shilpa Pharma’s Portfolio of ADC Linker Contract Manufacturing in India
Shilpa Pharma provides a highly specialized CDMO portfolio focused on ADC linkers manufacturing in India, supporting global Antibody-Drug Conjugates (ADCs) manufacturers with scalable and compliant solutions.
Our linker capabilities include:
✔ Cleavable ADC Linkers
Designed for controlled intracellular drug release via enzymatic or pH-based mechanisms.
✔ Non-Cleavable ADC Linkers
Engineered for enhanced plasma stability and predictable payload delivery.
✔ Hydrophilic & PEG-Based Linkers
Optimized to improve ADC solubility, pharmacokinetics, and therapeutic index.
✔ Custom & Proprietary Linkers
Co-development and bulk manufacturing of novel or client-specific linker chemistries tailored to unique ADC constructs.
Each linker category is supported by advanced analytical development, impurity control, stability studies, and process optimization, ensuring consistent quality and regulatory-ready supply. Shilpa Pharma is a trusted partner for ADC manufacturers in India seeking long-term, commercial-scale linker solutions.
Shilpa Pharma – Leading ADC Linkers Manufacturing Company in India
Shilpa Pharma is a globally trusted ADC Linkers Manufacturing Company in India, offering end-to-end CDMO services for pharmaceutical and biotech companies engaged in antibody-drug conjugate (ADC) development. With decades of experience in complex chemistry and regulated manufacturing, we support international partners seeking a reliable, scalable, and compliant CDMO in India for ADC linker development and commercial supply.
Our state-of-the-art cGMP facilities are approved by USFDA, EU GMP, ANVISA, COFEPRIS, TGA, PMDA, and KFDA, enabling seamless technology transfer and uninterrupted supply to regulated global markets. As one of the most trusted ADC linkers manufacturers in India, we provide development-to-commercial solutions covering process optimization, impurity control, analytical validation, and bulk manufacturing under stringent quality systems.
Shilpa Pharma’s integrated CDMO model aligns ADC linkers, payloads, and conjugation requirements to support efficient ADC drug development. With strong scientific expertise, regulatory-ready documentation, and secure global logistics, we enable international innovators to accelerate timelines, reduce risk, and scale confidently. This makes Shilpa Pharma a preferred ADC CDMO partner in India for global ADC manufacturers and oncology-focused biopharmaceutical companies.
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Everything You Need to Know About API Manufacturing in India at Shilpa Pharma
What are ADC linkers and why are they critical in ADC development?
ADC linkers are chemical components that connect the antibody to the cytotoxic drug in an Antibody-Drug Conjugate. They control payload stability in circulation and drug release at the target site, directly impacting ADC safety and efficacy.
Is Shilpa Pharma a manufacturer of ADC linkers in India?
Yes. Shilpa Pharma is a leading ADC linkers manufacturer in India, offering cGMP-compliant development and large-scale manufacturing for global pharmaceutical and biotech companies.
What types of ADC linkers does Shilpa Pharma manufacture?
Shilpa Pharma manufactures cleavable, non-cleavable, PEG-based, and custom antibody-drug conjugate linkers, supporting diverse ADC design and therapeutic strategies.
Are Shilpa Pharma’s ADC linkers suitable for regulated markets?
Yes. All ADC linkers are manufactured in cGMP facilities approved by USFDA, EU GMP, ANVISA, COFEPRIS, TGA, PMDA, and KFDA, ensuring global regulatory acceptance.
How does Shilpa Pharma support antibody-drug conjugate (ADC) development?
Shilpa Pharma supports ADC development through integrated linker chemistry, process optimization, impurity profiling, analytical characterization, and scalable manufacturing.
Can Shilpa Pharma develop custom ADC linkers?
Yes. Shilpa Pharma offers custom ADC linker development, including co-development of proprietary linker chemistries tailored to specific payloads, antibodies, and conjugation methods.
Why choose an ADC linkers manufacturer in India for global programs?
ADC manufacturers in India offer cost efficiency, scalability, and regulatory compliance. Shilpa Pharma combines these advantages with advanced HPAPI Â infrastructure and global CDMO expertise.
Does Shilpa Pharma support clinical and commercial ADC programs?
Yes. Shilpa Pharma supports ADC programs from early clinical development through long-term commercial supply with validated, scalable manufacturing processes.
How does Shilpa Pharma ensure quality and consistency in ADC linkers?
Quality is ensured through advanced analytical controls, impurity and stability testing, validated processes, and strict adherence to global cGMP standards.
Who partners with Shilpa Pharma for ADC linkers manufacturing?
Global pharmaceutical companies, biotechnology firms, and ADC manufacturers partner with Shilpa Pharma for reliable, compliant, and scalable ADC linker manufacturing.
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Learn About ADC Linkers
Antibody Drug Conjugates (ADCs) have revolutionized targeted cancer therapy by combining the specificity of antibodies with the potency of cytotoxic drugs. At the heart of these innovative therapies lie ADC linkers, critical components that connect the drug to the antibody, ensuring precise delivery to cancer cells while minimizing damage to healthy tissue.
What Are ADC Linkers?
ADC linkers, also known as antibody drug conjugate linkers, are specialized molecules that securely attach the cytotoxic drug (also called the payload) to the antibody. These linkers play a vital role in maintaining the stability of the conjugate while circulating in the bloodstream and releasing the drug only at the target site.
Types of Drug Linkers
One of the most common types of linkers used in ADCs is the protease cleavable linker. These linkers are designed to be stable in the bloodstream but cleaved by specific enzymes (proteases) that are abundant in cancer cells. This selective cleavage ensures that the cytotoxic drug is released precisely where it is needed, enhancing the efficacy and safety of the therapy.
Why Choose Shilpa as Your ADC Linkers Manufacturer in India?
As leading ADC linkers manufacturers in India, Shilpa Pharma is committed to delivering high-quality, reliable, and innovative drug linkers for the pharmaceutical and biotech industries. Our advanced manufacturing processes and strict quality control ensure that our ADC linkers meet the highest standards for research and clinical use.
By partnering with Shilpa, you gain access to cutting-edge linker technologies, including a range of protease cleavable linkers and other custom solutions designed to meet your specific requirements.
